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1

Differential pharmacokinetic interaction of cyclosporine and tacrolimus with colchicine in renal allograft recipients

Beaudreuil, Severine, Schermann, Jean Michel, Verstuyft, Céline, Barrail-Tran, Aurelie, Smirnova, Maria, Durrbach, Antoine, Becquemont, Laurent

Journal:

Clinical Transplantation

Year:

2018

Language:

english

File:

PDF, 366 KB

english, 2018

2

Social Darwinism: from reality to myth and from myth to reality

Daniel Becquemont

Journal:

Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences

Year:

2011

Language:

english

File:

PDF, 180 KB

english, 2011

3

Erythromycin Infusion Prior to Endoscopy for Acute Upper Gastrointestinal Bleeding: A Randomized, Controlled, Double-Blind Trial

Carbonell, Nicholas, Pauwels, Arnaud, Serfaty, Lawrence, Boelle, Pierre-Yves, Becquemont, Laurent, Poupon, Raoul

Journal:

American Journal of Gastroenterology

Year:

2006

Language:

english

File:

PDF, 78 KB

english, 2006

4

Le métabolome plasmatique humain : valeurs de référence chez 800 volontaires sains ; impact du cholestérol, du genre et de l’âge

Trabado, S., Al-Salameh, A., Croixmarie, V., Masson, P., Corruble, E., Feve, B., Colle, R., Ripoll, L., Walther, B., Boursier-Neyret, C., Werner, E., Becquemont, L., Chanson, P.

Journal:

Annales d'Endocrinologie

Year:

2016

Language:

french

File:

PDF, 177 KB

french, 2016

5

Commentaire sur Delisle. Les philosophies du néo-darwinisme

Becquemont, Daniel

Journal:

Year:

2011

Language:

french

File:

PDF, 148 KB

french, 2011

6

Contrôle insuffisant des facteurs de risque cardiovasculaire chez les femmes diabétiques âgées en soins primaires

Al-Salameh, A., Bucher, S., Becquemont, L., Ringa, V.

Journal:

Revue d'Épidémiologie et de Santé Publique

Year:

2016

Language:

french

File:

PDF, 144 KB

french, 2016

7

National Observatory on the Therapeutic Management in Ambulatory Care Patients Aged 65 and Over, with Type 2 Diabetes, Chronic Pain or Atrial Fibrillation

Becquemont, Laurent, Benattar-Zibi, Linda, Bertin, Philippe, Berrut, Gilles, Corruble, Emmanuelle, Danchin, Nicolas, Delespierre, Tiba, Derumeaux, Geneviève, Falissard, Bruno, Forette, Francoise, Hano

Journal:

Year:

2013

File:

PDF, 691 KB

2013

8

Type 1 Gaucher disease (CYP2D6-eliglustat)

Becquemont, Laurent

Journal:

Year:

2017

Language:

english

File:

PDF, 365 KB

english, 2017

9

La médecine personnalisée : comment passer du concept à l’intégration dans un plan de développement clinique en vue d’une AMM ?

Becquemont, Laurent, Bordet, Régis, Cellier, Dominic, Bardou, Marc, Beaune, Philippe, Belorgey, Chantal, Bibeau, Frédéric, Boissel, Jean-Pierre, Courcier, Soizic, De Broucker, Frédérique, Demotes-Main

Journal:

Year:

2012

Language:

french

File:

PDF, 513 KB

french, 2012

10

The CGGGG insertion/deletion polymorphism of the IRF5 promoter is a strong risk factor for primary Sjögren's syndrome

Corinne Miceli-Richard, Nicolas Gestermann, Marc Ittah, Emmanuelle Comets, Pascale Loiseau, Xavier Puechal, Eric Hachulla, Jacques-Eric Gottenberg, Pierre Lebon, Laurent Becquemont, Xavier Mariette

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 91 KB

english, 2009

11

Phase I and Phase II drug-metabolizing enzymes are expressed and heterogeneously distributed in the biliary epithelium

Fatima Lakehal, Dominique Wendum, Véronique Barbu, Laurent Becquemont, Raoul Poupon, Pierre Balladur, Laurent Hannoun, François Ballet, Philippe H. Beaune, Chantal Housset

Journal:

Year:

1999

Language:

english

File:

PDF, 679 KB

english, 1999

12

Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4–dependent pharmacokinetics in humans

BECQUEMONT, L, GLAESER, H, DRESCHER, S, HITZL, M, SIMON, N, MURDTER, T, HEINKELE, G, HOFMANN, U, SCHAEFER, C, BURK, O

Journal:

Clinical Pharmacology & Therapeutics

Year:

2006

Language:

english

File:

PDF, 340 KB

english, 2006

13

La co-administration de MTX au cours de la PR augmente significativement la réponse ACR50 à l'adalimumab (Etude ReAct) indépendamment des polymorphismes des gènes MDR1 (multidrug resistance 1) et MTHFR (methylenetetrahydrofolate reductase)

C. Miceli-Richard, C. Verstuyft, E. Comets, P. Ravaud, H. Kupper, L. Becquemont, X. Mariette

Journal:

Revue du Rhumatisme

Year:

2006

Language:

french

File:

PDF, 136 KB

french, 2006

14

Effect of grapefruit juice on digoxin pharmacokinetics in humans

BECQUEMONT, L, VERSTUYFT, C, KERB, R, BRINKMANN, U, LEBOT, M, JAILLON, P, FUNCKBRENTANO, C

Journal:

Clinical Pharmacology & Therapeutics

Year:

2001

Language:

english

File:

PDF, 858 KB

english, 2001

15

Influence of the CYP1A2 inhibitor fluvoxamine on tacrine pharmacokinetics in humans*

Becquemont, Laurent, Ragueneau, Isabelle, Bot, Marie Annick Le, Riche, Christian, Funck-Brentano, Christian, Jaillon, Patrice

Journal:

Clinical Pharmacology & Therapeutics

Year:

1997

Language:

english

File:

PDF, 911 KB

english, 1997

16

Variability of cytochrome P450 1A2 activity over time in young and elderly healthy volunteers

T. Simon, L. Becquemont, B. Hamon, E. Nouyrigat, Y. Chodjania, J. M. Poirier, C. Funck-Brentano, P. Jaillon

Journal:

British Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 60 KB

english, 2001

17

Frequency of cytochrome P450 2C9 allelic variants in the Chinese and French populations

Jue Quin Yang, Sandrine Morin, Céline Verstuyft, Li An. Fan, Yong Zhang, Chun Di Xu, Véronique Barbu, Patrice Jaillon, Laurent Becquemont

Journal:

Fundamental & Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 63 KB

english, 2003

18

Biochemical and analytical development of the CIME cocktail for drug fate assessment in humans

Orianne Videau, Marcel Delaforge, Mikael Levi, Etienne Thévenot, Olivier Gal, Laurent Becquemont, Philippe Beaune, Henri Bénech

Journal:

Rapid Communications in Mass Spectrometry

Year:

2010

Language:

english

File:

PDF, 310 KB

english, 2010

19

Genetic and environmental risk factors for oral anticoagulant overdose

C. Verstuyft, A. Robert, S. Morin, M. A. Loriot, A. Flahault, P. Beaune, C. Funck-Brentano, P. Jaillon, L. Becquemont

Journal:

European Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 200 KB

english, 2003

20

Digoxin pharmacokinetics andMDR1genetic polymorphisms

Céline Verstuyft, Mathias Schwab, Elke Schaeffeler, Reinhold Kerb, Ulrich Brinkmann, Patrice Jaillon, Christian Funck-Brentano, Laurent Becquemont

Journal:

European Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 179 KB

english, 2003

21

Measurement of CYP2D6 and CYP3A4 activity in vivo with dextromethorphan: sources of variability and predictors of adverse effects in 419 healthy subjects

Christian Funck-Brentano, Pierre-Yves Boëlle, Céline Verstuyft, Célia Bornert, Laurent Becquemont, Jean-Marie Poirier

Journal:

European Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 297 KB

english, 2005

22

Modelling the influence of MDR1 polymorphism on digoxin pharmacokinetic parameters

Emmanuelle Comets, Céline Verstuyft, Marc Lavielle, Patrice Jaillon, Laurent Becquemont, France Mentré

Journal:

European Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 324 KB

english, 2007

23

Evidence for a pharmacogenetic adapted dose of oral anticoagulant in routine medical practice

Laurent Becquemont

Journal:

European Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 192 KB

english, 2008

24

Is diclofenac a valuable CYP2C9 probe in humans?

S. Morin, M.A. Loriot, J.M. Poirier, L. Tenneze, P.H. Beaune, C. Funck-Brentano, P. Jaillon, L. Becquemont

Journal:

European Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 98 KB

english, 2001

25

Identifying and preventing adverse drug events in elderly hospitalised patients: A randomised trial of a program to reduce adverse drug effects

Christophe Trivalle, T. Cartier, C. Verny, A. -M. Mathieu, P. Davrinche, H. Agostini, L. Becquemont, P. Demolis, The Imepag Group

Journal:

The Journal of Nutrition, Health & Aging

Year:

2010

Language:

english

File:

PDF, 173 KB

english, 2010

26

Un haplotype du gène du TNF alpha influence la réponse à l'adalimumab chez les patients atteints de polyarthrite rhumatoïde

C. Miceli-Richard, E. Comets, C. Verstuyft, P. Loiseau, R. Tamouza, P. Ravaud, H. Kupper, L. Becquemont, P. Charron, X. Mariette

Journal:

Revue du Rhumatisme

Year:

2006

Language:

french

File:

PDF, 59 KB

french, 2006

27

Gefitinib–phenytoin interaction is not correlated with the 14C-erythromycin breath test in healthy male volunteers

Stephanie Chhun, Celine Verstuyft, Nathalie Rizzo-Padoin, Guy Simoneau, Laurent Becquemont, Ilana Peretti, Alan Swaisland, Robert Wortelboer, Jean Francois Bergmann, Stephane Mouly

Journal:

British Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 910 KB

english, 2009

28

Amoxicillin/clavulanic acid-warfarin drug interaction: a randomized controlled trial

Qian Zhang, Guy Simoneau, Celine Verstuyft, Ludovic Drouet, Claire Bal dit Sollier, Jean-Claude Alvarez, Nathalie Rizzo-Padoin, Jean Francois Bergmann, Laurent Becquemont, Stéphane Mouly

Journal:

British Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 586 KB

english, 2011

29

Impact of genetic factors (VKORC1, CYP2C9, CYP4F2 and EPHX1) on the anticoagulation response to fluindione

Karine Lacut, Estelle Ayme-Dietrich, Lenaick Gourhant, Elise Poulhazan, Marion Andro, Laurent Becquemont, Dominique Mottier, Gregoire Le Gal, Celine Verstuyft

Journal:

British Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.73 MB

english, 2012

30

Mibefradil, a potent CYP3A inhibitor, does not alter pravastatin pharmacokinetics

Laurent Becquemont, Christian Funck-Brentano, Patrice Jaillon

Journal:

Fundamental & Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 384 KB

english, 1999

31

Low levels of lymphocyte MDR1 gene expression during early renal transplantation in patients treated with tacrolimus

Laurent Becquemont, Maryse Camus, Faical Kriaa, Véronique Barbu, Bernard Charpentier, Patrice Jaillon

Journal:

Fundamental & Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 375 KB

english, 2000

32

Lymphocyte P-glycoprotein expression and activity before and after rifampicin in man

Laurent Becquemont, Maryse Camus, Valérie Eschwege, Véronique Barbu, Elisabeth Rey, Christian Funck-Brentano, Patrice Jaillon

Journal:

Fundamental & Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 552 KB

english, 2000

33

ERRATUM

J. Q. Yang, S. Morin, C. Verstuyft, L. A. Fan, Y. Zhang, ChP. Xu, V. Barbu, C. Funck-Brentano, P. Jaillon, L. Becquemont

Journal:

Fundamental & Clinical Pharmacology

Year:

2004

File:

PDF, 199 KB

2004

34

The antinociceptive effect and adverse drug reactions of oxycodone in human experimental pain in relation to genetic variations in the OPRM1 and ABCB1 genes

Stine T. Zwisler, Thomas P. Enggaard, Lene Noehr-Jensen, Soeren Mikkelsen, Céline Verstuyft, Laurent Becquemont, Soeren H. Sindrup, Kim Brosen

Journal:

Fundamental & Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 209 KB

english, 2010

35

Vitamin K epoxide reductase genetic polymorphism is associated with venous thromboembolism: results from the EDITH Study

K. LACUT, C. LARRAMENDY-GOZALO, G. LE GAL, J. DUCHEMIN, B. MERCIER, L. GOURHANT, D. MOTTIER, L. BECQUEMONT, E. OGER, C. VERSTUYFT

Journal:

Journal of Thrombosis and Haemostasis

Year:

2007

Language:

english

File:

PDF, 486 KB

english, 2007

36

Cytochrome P4502C9 (CYP2C9) Genotypes in a Nordic Population in Denmark

Rasmus Steen Pedersen, Céline Verstuyft, Laurent Becquemont, Patrice Jaillon, Kim Brøsen

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2004

Language:

english

File:

PDF, 50 KB

english, 2004

37

Genetic Polymorphism of Vitamin K Epoxide Reductase (VKORC1) 1173C>T in a Chinese and a Caucasian Population

Claire Larramendy-Gozalo, Jue Quin Yang, Céline Verstuyft, Laurent Bodin, Liliane Dubert, Yong Zhang, Chundi Xu, Lian Fan, Patrice Jaillon, Laurent Becquemont

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2006

Language:

english

File:

PDF, 72 KB

english, 2006

38

Influence of CYP3A5 Genetic Polymorphism on Tacrolimus Daily Dose Requirements and Acute Rejection in Renal Graft Recipients

Lina Quteineh, Céline Verstuyft, Valerie Furlan, Antoine Durrbach, Alexia Letierce, Sophie Ferlicot, Anne-Marie Taburet, Bernard Charpentier, Laurent Becquemont

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2008

Language:

english

File:

PDF, 122 KB

english, 2008

39

Pharmacogenetics of Toxicity, Plasma Trough Concentration and Treatment Outcome with Nevirapine-Containing Regimen in Anti-Retroviral-Naïve HIV-Infected Adults: An Exploratory Study of the TRIANON ANRS 081 Trial

Claire Gozalo, Laurence Gérard, Pascale Loiseau, Laurence Morand-Joubert, Gilles Peytavin, Jean-Michel Molina, Pierre Dellamonica, Laurent Becquemont, Jean-Pierre Aboulker, Odile Launay, Céline Verstu

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2011

Language:

english

File:

PDF, 239 KB

english, 2011

40

Variable disposition kinetics and electrocardiographic effects of flecainide during repeated dosing in humans: Contribution of genetic factors, dose-dependent clearance, and interaction with amiodarone

Funck-Brentano, Christian, Becquemont, Laurent, Kroemer, Heyo K, Bühl, Kerstin, Knebel, Norbert G, Eichelbaum, Michel, Jaillon, Patrice

Journal:

Clinical Pharmacology & Therapeutics

Year:

1994

Language:

english

File:

PDF, 1.79 MB

english, 1994

41

Effect of NFE2L2 Genetic Polymorphism on the Association Between Oral Estrogen Therapy and the Risk of Venous Thromboembolism in Postmenopausal Women

Bouligand, J, Cabaret, O, Canonico, M, Verstuyft, C, Dubert, L, Becquemont, L, Guiochon-Mantel, A, Scarabin, P Y

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 118 KB

english, 2010

42

CYP2C9*3 Loss-of-Function Allele Is Associated With Acute Upper Gastrointestinal Bleeding Related to the Use of NSAIDs Other Than Aspirin

Carbonell, N, Verstuyft, C, Massard, J, Letierce, A, Cellier, C, Deforges, L, Saliba, F, Delchier, J C, Becquemont, L

Journal:

Clinical Pharmacology & Therapeutics

Year:

2010

Language:

english

File:

PDF, 144 KB

english, 2010

43

Amiodarone Interacts with Simvastatin but not with Pravastatin Disposition Kinetics

Becquemont, L, Neuvonen, M, Verstuyft, C, Jaillon, P, Letierce, A, Neuvonen, P J, Funck-Brentano, C

Journal:

Clinical Pharmacology & Therapeutics

Year:

2007

Language:

english

File:

PDF, 119 KB

english, 2007

44

Assessment of CYP2D6 and CYP2C19 activity in vivo in humans: A cocktail study with dextromethorphan and chloroguanide alone and in combination

TENNEZE, L, VERSTUYFT, C, BECQUEMONT, L, POIRIER, J, WILKINSON, G, FUNCKBRENTANO, C

Journal:

Clinical Pharmacology & Therapeutics

Year:

1999

Language:

english

File:

PDF, 53 KB

english, 1999

45

Effect of interferon α-ribavirin bitherapy on cytochrome P450 1A2 and 2D6 and N-acetyltransferase-2 activities in patients with chronic active hepatitis C*

Becquemont, Laurent, Chazouilleres, Olivier, Serfaty, Lawrence, Poirier, Jean Marie, Broly, Franck, Jaillon, Patrice, Poupon, Raoul, Funck-Brentano, Christian

Journal:

Clinical Pharmacology & Therapeutics

Year:

2002

Language:

english

File:

PDF, 603 KB

english, 2002

46

Halofantrine Metabolism in Microsomes in Man: Major Role of CYP 3A4 and CYP 3A5

B. BAUNE, J. P. FLINOIS, V. FURLAN, F. GIMENEZ, A. M. TABURET, L. BECQUEMONT, R. FARINOTTI

Journal:

Journal of Pharmacy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 122 KB

english, 1999

47

Prolonged sedation requiring mechanical ventilation and continuous flumazenil infusion after routine doses of clorazepam for alcohol withdrawal syndrome

Guglielminotti, J., Maury, E., Alzieu, M., Delhotal Landes, B., Becquemont, L., Guidet, B., Offenstadt, G.

Journal:

Intensive Care Medicine

Year:

1999

Language:

english

File:

PDF, 36 KB

english, 1999

48

CO.51 Importance du variant allélique CYP2C9*3 chez les patients présentant une hémorragie gastro-intestinale liée aux AINS

N. Carbonell, C. Verstuyft, J. Massard, A. Letierce, C. Cellier, L. Deforges, F. Saliba, J.C. Delchier, D. Thabut, L. Becquemont

Journal:

Gastroentérologie Clinique et Biologique

Year:

2009

Language:

french

File:

PDF, 93 KB

french, 2009

49

Influence of fluvoxamine on tacrine metabolism in vitro: potential implication for the hepatotoxicity in vivo

L. Becquemont, MA Le Bot, C. Riche, P. Beaune

Journal:

Fundamental & Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 139 KB

english, 1996

50

Pharmacogénétique au service du bon usage du médicament

Journal:

La Revue de Médecine Interne

Year:

2009

Language:

french

File:

PDF, 117 KB

french, 2009

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